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  • Shift of spatial representation from near Te in the target-aligned fixed window analysis toward Ge in saccade-aligned fixed window analysis of reactive task data. Each row shows the raster/spike density plot and best fit RF for an example neuron, followed the distribution of T-G α values of full population.
    Transforming Vision Into Brainstem Commands for Gaze Direction
  • Predicting Future Diagnosis from Brain Data Alone
  • Image of sets of data collected and analyzed by Emily Hill.
    Tracking Tau Oligomer-Induced Pathology in Single Neuronal Cells
  • Seven panelists sit at a table discussing social issues at Neuroscience 2019
    Ethical and Social Issues Raised by Neural-Digital Interfaces
  • A panelist speaks at a podium at a professional development workshop at Neuroscience 2019.
    Teaching Computation in Neuroscience
  • Scientific Image
    Epigenetics in Neurobiology Lightning Talks
  • Optogenetic stimulation of the RE/CB reliably produces an evoked potential in the HPC.
    The Thalamic Nucleus Reuniens Orchestrates Prefrontal-Hippocampal Slow-Waves
  • Scientific Image
    Epigenetics in Neurobiology
    April 08, 2020 11:00 AM - 4:00 PM EDT
  • Movement trajectories are idiosyncratic between subjects, yet consistent within subject. Layout of the start position (green filled circle), and short (blue filled circle) and long targets (red filled circle) is the same as in Figure 1C. Color-coding of traces reflects hand movement through the progression of the given trial (black, warm-up period; green, during the tone duration; red, after the tone until the decision). Top row, Trajectory data for 2000 ms trials for three example subjects from Experiment 1 (free-movement). Classification of a short duration is the left target; a long classification is the right target. Each subject employed a separate strategy, with one subject (S4) moving in a circular pattern between short and long locations, another (S1) rotating in a leftward arc before moving in between both targets, and a third (S2) moving in an up–down fashion before shifting from the middle to a target location. Bottom row, Three example subjects for 2000 ms trials from Experiment 2 (hold). Changes-of-mind are evident, including a shift from long to short (S1), short to long (S3), and both (S2).
    Motor and Action Planning Enhance How We Make Decisions About Time Duration
  • Scientific Image
    Neuroethology: From Behavior to Brain Lightning Talks
  • This image shoes the relative KCC2 depletion in WT and CX3CR1 BDNF KO animals 14 d after cut/ligation. Genotype had no effect on KCC2 levels in motoneurons contralateral or ipsilateral to injury. Removing BDNF from microglia had no impact on KCC2 expression. Lumbar spinal cord sections from animals expressing normal CSF1 and with CSF1 removed from motoneurons 14 d after ligation. ChatIREScre/+: : csf1f/f animals exhibit normal microgliosis in the dorsal horn but have the microglial reaction to injury greatly attenuated in the ventral horn compared to ChatI+/+: : csf1f/f. KCC2 immunofluorescence 14 d after sciatic ligation in csf1f/f animals. Preventing microgliosis in the ventral horn had no impact on KCC2 within intact or injured motoneurons. Error bars = SEM; **p ≤ 0.01, ***p ≤ 0.001.
    KCC2 on Axotomized Motoneurons Is Regulated Differently Than in Systems Previously Described
  • This image shows the total persistent outward currents and lamotrigine-sensitive K+ currents in TG neurons from WT, HET, and TRESK KO mice.
    Loss of TRESK Potassium Channel Causes Headache but Not Body Pain
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