Material below summarizes the article Layer 5 Corticofugal Projections from Diverse Cortical Areas: Variations on a Pattern of Thalamic and Extrathalamic Targets, published on July 22, 2020, in JNeurosci and authored by Judy A. Prasad, Briana J. Carroll and S. Murray Sherman
Highlights
- Across cortical areas, layer 5 neurons exhibit a general pattern of targeting both thalamus and extra-thalamic regions, including brainstem motor centers.
- Variations on the layer 5 efferent pattern depend on cortical area.
- Layer 5 terminals also vary in size, depending on cortical area and subcortical target.
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