Material below summarizes the article Functional Integration of Adult-Born Hippocampal Neurons after Traumatic Brain Injury, published on September 14, 2015, in eNeuro and authored by Laura E. Villasana, Kristine N. Kim, Gary L. Westbrook, and Eric Schnell.
Although the majority of neurons in mammalian brains are generated during embryologic development, the production of new neurons continues throughout life in at least two brain regions in a process known as adult neurogenesis. These adult-born neurons integrate into neuronal circuits and are believed to play an important role in brain function. In the hippocampus, new granule cells are born in adult animals and contribute to learning and memory. Interestingly, the production of these adult-born granule cells increases markedly after certain forms of neuronal injury, including seizures, strokes, and traumatic brain injury (TBI). It has been hypothesized that these new neurons might play a role in recovery.
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