Material below summarizes the article Mitochondrial Ultrastructure Is Coupled to Synaptic Performance at Axonal Release Sites, published on January 15, 2018, in eNeuro and authored by Csaba Cserép, Balázs Pósfai, Anett Dóra Schwarcz, and Ádám Dénes.
Synaptic transmission, the process through which brain cells communicate with each other, consumes a huge amount of energy, the vast majority of which is provided by neuronal mitochondria.
As information is being processed and stored in the brain, long-term changes occur in synaptic strength, altering both the structure and the activity of these connections. This means the amount of energy needed at a given location in neural networks is also changing in space and time, making some kind of adaptation mechanism necessary.
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