Despite many challenges, the last decade has seen tremendous progress in neuroscience. To support continued progress, the National Institutes of Health (NIH) has taken a lead role in implementing the President's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Francis Collins, the NIH director, discusses how his agency, working with the neuroscience community, is catalyzing development of technologies to provide dynamic pictures of the brain, both in disease and in health. Collins also examines challenges that cut across biomedical disciplines, and reflect upon opportunities for neuroscientists to face such challenges and generate tomorrow's advances.
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