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Headshot of Erica Tracey Akhter

Erica Tracey Akhter, PhD

Erica Tracey Akhter is an instructor at Georgia State University. She obtained her PhD from Emory University, where she worked on the topic of this article and looked for novel mechanisms driving motor axon regeneration. She defended her thesis work in 2019.

By This Contributor

  • This image shoes the relative KCC2 depletion in WT and CX3CR1 BDNF KO animals 14 d after cut/ligation. Genotype had no effect on KCC2 levels in motoneurons contralateral or ipsilateral to injury. Removing BDNF from microglia had no impact on KCC2 expression. Lumbar spinal cord sections from animals expressing normal CSF1 and with CSF1 removed from motoneurons 14 d after ligation. ChatIREScre/+: : csf1f/f animals exhibit normal microgliosis in the dorsal horn but have the microglial reaction to injury greatly attenuated in the ventral horn compared to ChatI+/+: : csf1f/f. KCC2 immunofluorescence 14 d after sciatic ligation in csf1f/f animals. Preventing microgliosis in the ventral horn had no impact on KCC2 within intact or injured motoneurons. Error bars = SEM; **p ≤ 0.01, ***p ≤ 0.001.
    KCC2 on Axotomized Motoneurons Is Regulated Differently Than in Systems Previously Described
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