This event took place on September 27, 2019 and is no longer available on-demand.
The ability to create pluripotent stem cells from human cells has radically changed the landscape of studying the mechanisms of human diseases. Induced pluripotent stem cells (iPSCs), organoid technology, and cellular reprogramming methods are providing new insight into how the brain develops, matures, and ages, and how these patterns are altered by neurological disorders. By using human cells rather than animal models, these techniques allow researchers to better capture the genetic diversity of the human population. This virtual conference will explore how leaders in the field are using cellular reprogramming methods to understand the genetic, molecular, and cellular underpinnings of neurological disorders, as well as to screen for potential treatments.
This virtual conference serves as a complement to SfN’s Training Series: Stem Cells and Reprogramming Methods for Neuroscience. While it is recommended you view some resources before attending the virtual conference, you can participate without doing so.
Watch short videos from neuroscientists in the field as they describe important methods, concepts, and data from their lab. The videos are available on Neuronline.
Continue the conversation in our Community Discussion.
Contact us if you have questions. Email firstname.lastname@example.org or call (202) 962-4000.
This conference is intended to be applicable to individuals who are interested in development and use of iPSCs, organoids, or other in vitro models used in neuroscience research.
- Hear from leaders in the field and gain new insight for your research.
- Ask questions and get answers from experts — each session will be accompanied by a Q&A opportunity.
- Network with other attendees from around the world in the interactive networking lounge.
- Avoid travel costs and learn about cutting-edge research from the comfort of your home, classroom, or lab.
- Host watch parties with students and colleagues — only one registration is required. Please find information about watching in a group and using second screen participation links for individuals who are not registered here.
- Enjoy six months of on-demand access. Can’t make it for the live day or want to watch the talks again? All sessions and data blitz videos are immediately available on demand.
Click on each session title to reveal its description.
Speakers: Kristin Baldwin and Lorenz Studer
Time: 11 a.m. – noon EDT
Reprogramming methods, including induced pluripotent stem cells (iPSCs) and organoid cultures, have opened new doors into modeling human disease in the culture dish. Lorenz Studer and Kristin Baldwin will discuss new developments in cellular reprogramming methods and technologies, while also addressing the challenges and opportunities that lie ahead for the field.
Speakers: Guo-li Ming and Arnold Kriegstein
Time: 12:15 – 1:15 EDT
Three-dimensional (3D) organoid cultures from human induced pluripotent stem cells enable a comprehensive study of the development and cytoarchitecture of the human brain. In this session, Arnold Kriegstein will discuss the cellular diversity of cerebral organoids and the effect of metabolic stress on organoid cultures. Then, Guo-li Ming will share the advances her lab has made in producing brain-region specific organoids and furthering their maturation to model human brain development.
Speakers: Silvia Cappello and Marius Wernig
Time: 1:30 – 2:30 EDT
Cellular reprogramming methods allow for the creation of human disease models that more closely mimic the molecular and cellular mechanisms of neurodevelopmental and neuropsychiatric disorders than mouse homologues. In this session, Silvia Capello will discuss how the use of human-derived cerebral organoids allows her lab to investigate the mechanisms of neuronal migration during development. Then, Marius Wernig will explore how his lab is using reprogrammed patient donor cells to study the role of a mutation in a synaptic cell-adhesion molecule in autism spectrum disorders.
Speakers: Justin Ichida and Paul Tesar
Time: 2:45 – 3:45 EDT
Stem cell and reprogramming technologies provide unprecedented access to disease-relevant cells and tissues to create in vitro models of human neurodegenerative diseases. These cellular technologies enable large-scale, in vitro screening of drug-like compounds to identify potential therapeutics. Justin Ichida will discuss his lab’s work on screening for drugs that enhance the survival of motor neurons for diseases like amyotrophic lateral sclerosis (ALS), and Paul Tesar will share his lab’s work on screening for drugs that stimulate regeneration of myelin in disease like multiple sclerosis.
Speakers: Hideyoku Okano and Tracy Young-Pearse
Time: 4 – 5 EDT
Induced pluripotent stem cells generated from patient populations have become a key tool for understanding the genetics of neurodegenerative disorders such as ALS and Alzheimer’s disease (AD). Hideyuki Okano will discuss how his lab classifies the genomic and phenotypic characteristics of iPSCs generated from patients with sporadic ALS. Then, Tracy Young-Pearse will present her lab’s work on generating iPSC lines from deeply phenotyped cohorts to study late-onset AD.
Data Blitz Sessions
This virtual conference will include short data blitz videos accessible to attendees. These videos feature neuroscientists in the field providing a research summary. The videos are available on demand, so you can watch them throughout the live day or after the conference.
Data blitz videos will be provided by: Shan Bian, Fred Etoc, Evangelos Kiskinis, Pedro Rifes, Ryan Smith & Kosuke Funato, Faranak Fattahi, Hiroko Nobuta, and Iva Kelava
- Presentations and Q&A Sessions: Watch presentations and ask speakers your questions live during the virtual conference. View the agenda for a full list of speakers and sessions.
- Data Blitzes: Watch short videos on research related to the conference topic at any point after the virtual conference environment opens.
- Networking Lounge: Meet colleagues and conference faculty in the virtual lounge.
- Resources: Download additional information and resources chosen by speakers.
- Trivia: Play a game to test your knowledge.
- Exhibits: Explore booths to learn more about the Annual Meeting and Neuronline.
- On-Demand Access: All sessions and data blitz videos are available on demand for six months following the conference.
Review SfN’s Code of Conduct, rules for virtual events in the Digital Learning Community Guidelines, and communications policies regarding dissemination of unpublished scientific data, listed below. SfN asks that conference attendees respect the sensitivity of information and data being presented that are not yet available to the public by following these guidelines:
- Do not capture or publicly share details of any unpublished data presented.
- If you are unsure whether data is unpublished, check with the presenter.
- Respect presenters' wishes if they indicate that the information presented is not to be shared.
When will the conference open? The conference will open for registrants on Friday, September 27, at 10:30 a.m. Sessions will run live from 11 a.m. to 5 p.m. EDT.
How long is the conference available on demand? After the live day, each conference will be available on demand for six months.
How do I access the conference on the live day and on demand? To enter the conference either live or on demand, use the login button found in your registration confirmation email and enter your email address in lowercase letters. Your login information should not be shared and can only be entered by one person at a time. You may access the conference as many times as you would like.
How can I broadcast the event to a group and allow group viewers to participate in the sessions? A virtual conference access link can be used to broadcast the event on one device at a time. Please find information about watching in a group and using second screen participation links for individuals who are not registered here.
How do I find my receipt for the virtual conference? Receipt information is included in your registration confirmation email.