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Join speakers Costas Arvanitis, Sreekanth Chalasani, and Hong Chen as they present new frontiers in neuroscience techniques: the applications of ultrasound for neuroscience research. With moderator Elizabeth Glater, these experts will provide an overview of ultrasound techniques, as well as applications in research, diagnostics, and therapeutics. They will address both challenges and successful strategies for integrating the fields of neuroscience, molecular biology, and engineering.
Learning Objectives:
1. Overview of the use of ultrasound in neuroscience
2. Utility of ultrasound in research, diagnosis and therapies
3. Overview of sonogenetics
4. Discuss the interaction of ultrasound and the neurovascular unit and its role in therapy
Speakers
Costas Arvanitis, PhD
Costas Arvanitis, PhD, is a joint associate professor at the Woodruff School of Mechanical Engineering and the Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University). Arvanitis completed his doctoral studies at University College London at the Department of Medical Physics and Bioengineering in 2008. Subsequently, he did a two-year postdoctoral fellowship (2008-2009) at the Institute of Biomedical Engineering at the University of Oxford. He then carried on with his research at Harvard Medical School and Brigham and Women’s Hospital (2010-2016), where he reached the rank of instructor. Arvanitis’ research integrates ultrasonics, quantitative imaging, mathematical modeling, and in vitro/in vivo experimentation to support the discovery and translation to the clinics of novel diagnostic and therapeutic interventions against brain diseases. Specific areas of his research include targeted cell and gene delivery, cell-based diagnostics and therapeutics, and image guided therapy.
Sreekanth Chalasani, PhD
Sreekanth Chalasani, PhD, is a professor in the Molecular Neurobiology Laboratory at the Salk Institute. He has pioneered the development of sonogenetics, where exogenous mechanosensitive channels are used to confer ultrasound responsiveness to target cells (sonogenetics.salk.edu). He has a PhD from the University of Pennsylvania and completed postdoctoral training at UCSF and Rockefeller University before starting his lab at the Salk Institute.
Hong Chen, PhD
Hong Chen, PhD, is an associate professor of biomedical engineering and neurosurgery at Washington University in St. Louis. She earned her PhD in bioengineering from the University of Washington in 2011. She completed postdoctoral training at Columbia University's Department of Biomedical Engineering (2012-2015). Since joining Washington University in 2015, Chen's research has centered on leveraging ultrasound technology for the non-invasive diagnosis and treatment of brain diseases and advancing the understanding of brain function. A recognized leader in the field of ultrasound, she holds key positions on several boards and committees. She serves on the Board of Directors for the International Society of Therapeutic Ultrasound, is a member of the IEEE International Ultrasonics Technical Committee and contributes to the Acoustical Society of America's Biomedical Ultrasound Technical Committee. Chen is a senior member of the National Academy of Inventors and was recently honored with the NIH Director’s Pioneer Award.
Elizabeth Glater, PhD
Elizabeth Glater, PhD, is an associate professor of neuroscience at Pomona College, received her PhD in neuroscience from Harvard University and pursued postdoctoral work in Cori Bargmann’s lab at The Rockefeller University. Her research examines the ways the nervous system allows animals to generate behavioral responses to their environment. Her laboratory uses the nematode Caenorhabditis elegans to investigate the genetic, chemical, and neuronal basis of food choice behavior.
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