The Thalamic Nucleus Reuniens Orchestrates Prefrontal-Hippocampal Slow-Waves
Feb 20, 2020
Material below summarizes the article The Reuniens Nucleus of the Thalamus Has an Essential Role in Coordinating Slow-Wave Activity Between Neocortex and Hippocampus, published on September 23, 2019, in eNeuro and authored by Brandon E. Hauer, Silvia Pagliardini, and Clayton T. Dickson.
Highlights
- Activity in the nucleus reuniens (RE) is related to slow sleep-related oscillations in two key episodic memory areas that it connects, the prefrontal cortex (PFC) and hippocampus (HPC).
- Selectively inhibiting the RE robustly impairs slow-wave coordination between PFC and HPC.
- Because slow-wave synchrony during sleep facilitates episodic memory, the RE is likely a key node in a PFC-HPC circuit promoting memory consolidation. Brandon Hauer
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About the Contributors
Brandon Hauer is a PhD candidate in Neuroscience at the University of Alberta, in Canada.
Silvia Pagliardini is associate professor of physiology and a member of the Neuroscience and Mental Health Institute at the University of Alberta.
Clayton Dickson is a professor of psychology and physiology and is the associate director of education at the Neuroscience and Mental Health Institute at the University of Alberta.
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