Material below is adapted from the SfN Short Course session Neuroinflammation and Neurosteroidogenesis: Reciprocal Modulation During Injury to the Adult Zebra Finch Brain, by Alyssa L. Pedersen, Jenna L. Brownrout, and Colin J. Saldanha. Short Courses are daylong scientific trainings on emerging neuroscience topics and research techniques held the day before the start of SfN’s annual meeting.
Steroid hormones have a wide-ranging influence on brain development and behavior. One hormone in particular — 17β-estradiol, also known as E2, which is made in the brain, ovaries, placenta, and fat tissue — can influence male and female sexual behaviors in adult and juvenile mammals. Studies have also shown recently that E2 can protect neurons and neural circuits, as well as influence neuroplasticity, in healthy and injured brains.
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