Material below summarizes the article Disrupted Prediction Error Links Excessive Amygdala Activation to Excessive Fear, published on January 13, 2016, in JNeurosciand authored by Auntora Sengupta, Bryony Winters, Elena E. Bagley, and Gavan P. McNally.
The amygdala, a group of nuclei in the medial temporal lobe, is a key brain structure for fear and anxiety. Several neuropsychiatric disorders are characterized by heightened activation of the amygdala. fMRI studies in clinically anxious people consistently show increased amygdala activity compared to controls during anxiety symptom provocation or presentations of negative emotional stimuli.
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