Material below summarizes the article Detailed Visual Cortical Responses Generated by Retinal Sheet Transplants in Rats With Severe Retinal Degeneration, published on December 12, 2018, in JNeurosci and authored by Andrzej T. Foik, Georgina A. Lean, Leo R. Scholl, Bryce T. McLelland, Anuradha Mathur, Robert B. Aramant, Magdalene J. Seiler, and David C. Lyon.
As humans, we rely heavily on vision. Defects in the retina can have major impacts and significantly worsen quality of life. One cause of vision loss is degeneration of photoreceptors, the cells in the retina that detect light. This occurs, for example, in people with age-related macular degeneration or retinitis pigmentosa. Many approaches have aimed to slow the loss of photoreceptors and ensuing blindness, but in some cases there are no longer sufficient photoreceptors to rescue. Therefore, the only chance to bring back vision is through injection of retinal progenitor cells or transplantation of healthy retinal sheets.
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