Material below summarizes the article Microglia Play an Active Role in Obesity-Associated Cognitive Decline, published on October 10, 2018, in JNeurosci and authoredby Elise C. Cope, Elizabeth A. LaMarca, Patrick K. Monari, Lyra B. Olson, Susana Martinez, Anna D. Zych, Nicole J. Katchur and Elizabeth Gould.
The World Health Organization has labeled obesity a global epidemic with major public health implications.
In humans, obesity produces many well-known health challenges, but one lesser-known danger is it diminishes cognitive function. Obesity also predisposes individuals to develop serious cognitive disorders later in life, such as dementia and Alzheimer's disease.
Neuroimaging studies have shown reduced brain volume in obese humans, particularly in areas that support cognitive function. Yet, the cellular processes underlying the association between obesity and neuronal structure remain elusive.
Access to the full article is available to SfN members.
Neuronline is a benefit of SfN membership. Renew your membership now to make sure you don’t lose access.