Harnessing Pluripotent Stem Cells to Study Neuropsychiatric Diseases
Material below is adapted from the SfN Short Course Developing Stem Cell Models to Study Neuropsychiatric Diseases, by Lindy Barrett, PhD, and Kevin Eggan, PhD. Short Courses are day-long scientific trainings on emerging neuroscience topics and research techniques held the day before SfN’s annual meeting.
Neuropsychiatric diseases are the leading cause of disability worldwide, affecting one in four people at some point in their lives. As a result of recent advances in DNA analysis technologies, scientists understand much more about the genetic basis of neuropsychiatric diseases such as schizophrenia, bipolar disorder, and autism spectrum disorder. However, the development of effective treatments for those disorders has been hindered by the lack of knowledge about how genetic variation affects the function of human brain cell types involved in behavior and cognition.
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