Scientific Research

From Data to Practice: Assessing New Alzheimer's Disease Therapies

December 17, 2024

12:00 PM - 1:00 PM EST

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Karl Herrup, Michelle Jin, and James Noble share their perspectives on evaluating the clinical impacts of emerging treatments for Alzheimer’s Disease. Attendees can submit questions at registration and live during the webinar.

Read two Commentaries informing this discussion:

Lecanemab and Donanemab as Therapies for Alzheimer's Disease: An Illustrated Perspective on the Data by Alberto J. Espay, Kasper P. Keep, and Karl Herrup
What's in It for Me? Contextualizing the Potential Clinical Impacts of Lecanemab, Donanemab, and Other Anti-β-amyloid Monoclonal Antibodies in Early Alzheimer's Disease by Michelle Jin and James M. Noble

Speakers

Karl Herrup, PhD

Karl Herrup is a professor of neurobiology at the University of Pittsburgh School of Medicine. Herrup previously served as the director of the Alzheimer's Research Center at Case Western Reserve University and the chair of cell biology and neuroscience at Rutgers University. His main research interests lie in the cell biology of neurodegenerative disease, with a focus on Alzheimer's disease. He received his PhD in neurobiology from Stanford University. He completed his postdoctoral training at Harvard Medical School and the Biozentrum in Basel Switzerland.

James Noble, MD, MS, CPH, FAAN

James Noble is an associate professor of neurology in the Taub Institute for Research on Alzheimer’s Disease and the Aging Brain at Columbia University Irving Medical Center (CUIMC). His clinical, research, outreach, advocacy, and education efforts are focused on modifiable risk factors of cognitive aging and improving awareness of neurological disorders. Noble is the clinical core leader of the Alzheimer’s Disease Research Center and directs several large programs funded by the National Institute of Aging. He sees patients in the CUIMC Aging & Dementia clinical practice where he also serves as a project lead in the Columbia CMS-GUIDE program. Additionally, he is co-editor of the standard text Merritt’s Neurology (Wolters-Kluwer 2021), the author of the caregiver handbook Navigating Life with Dementia (Oxford University Press/American Academy of Neurology 2022), and co-founder of Arts & Minds, a non-profit organization which provides art-centered museum based programs to persons with dementia and their care partners.

Michelle Jin, MS

Michelle Jin is an MD/PhD candidate enrolled in the Medical Scientist Training Program at Columbia University, Vagelos College of Physicians and Surgeons. Her doctoral research focuses on a comprehensive mapping of the behavioral and neural changes underlying sleep-wake disorders in an Alzheimer’s disease mouse model, as well as developing accessible methods for mapping and analysis of brain-wide activity in mice. Her work is supported by a predoctoral Ruth L. Kirschstein National Research Service Award from the National Institute on Aging. She earned her BA in biology and psychology from Cornell University in 2017 and previously receive a postbaccalaureate intramural research training fellowship to conduct research at the National Institute on Drug Abuse from 2017-2019.

Christophe Bernard, PhD

Christophe Bernard, PhD, is the PhysioNet team leader in at the Institute of Neuroscience Systems at the French Institute of Health and Medical Research (INSERM). His research focuses on understanding how physiological and pathological behaviors emerge from the organization and reorganization of the underlying neuronal architecture, with an emphasis on epilepsy. He currently serves as editor-in-chief of eNeuro.

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From Data to Practice: Assessing New Alzheimer's Disease Therapies

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