Distinct Genetic Signatures of Human Cortical and Subcortical Memory
May 07, 2020
Material below summarizes the article Distinct Genetic Signatures of Cortical and Subcortical Regions Associated with Human Memory, published on December 9, 2019, in eNeuro and authored by Pin Kwang Tan, Egor Ananyev, and Po-Jang Hsieh.
Highlights
- Despite a common involvement in memory, gene signatures of cortical and subcortical memory are largely distinct.
- Cortical memory genes are linked to immune and epigenetic regulation, while subcortical memory genes are associated with neurogenesis and the differentiation of glial cells.
- Overlapping genes between cortical and subcortical memory are involved in transcription regulation, synaptic plasticity, and glutamate receptor signaling.
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