Desire and Prediction: How Different Dopamine Signals Help Us Get What We Want
Material below summarizes the article Differential Dopamine Release Dynamics in the Nucleus Accumbens Core and Shell Reveal Complementary Signals for Error Prediction and Incentive Motivation, published on August 19, 2015, in JNeurosci and authored by Michael P. Saddoris, Fabio Cacciapaglia, R. Mark Wightman, and Regina M. Carelli.
Despite dopamine being one of the most actively studied neurotransmitters in the brain, there is surprisingly little consensus on what specifically this molecule contributes to behavior in normal animals.
One of the most dominant theories of dopamine signaling in the last 20 years has been based on the seminal work of Wolfram Schultz, whose experiments with dopamine neurons demonstrated a critical link between the firing patterns of dopamine neurons and learning.
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