Cerebral Organoids Grown From Stem Cells Offer a New Way to Study the Human Brain
Material below is adapted from the SfN Short Course Generating 3D Cerebral Organoids From Human Pluripotent Stem Cells to Model Cortical Development and Disease, by Paola Arlotta, PhD. Short Courses are daylong scientific trainings on emerging neuroscience topics and research techniques held the day before SfN’s annual meeting.
The human brain is a complex organ, and the most sophisticated part of it may be the cerebral cortex. Composed of billions of cells, multiple structural layers, and several different types of tissue, the cortex houses a diverse array of brain cell types, including nerve cells and supporting cells, or glia. In humans, the cortex processes information related to higher-order functions, such as thinking, sensory perception, and language.
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