Material below summarizes the article Astrogliosis Induced by Brain Injury is Regulated by Sema4B Phosphorylation, published on May 6, 2015, in eNeuro and authored by Liat Ben-Gigi, Sahar Sweetat, Elazar Besser, Yakov Fellig, Thorsten Wiederhold, Roberto D. Polakiewicz, and Oded Behar.
Astrocyte activation (reactive gliosis) accompanies most central nervous system (CNS) pathologies, including brain injury conditions. During astrocyte activation, the expression of many genes is modified, thus changing the cells’ protein expression profile and behavior.
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