In 2019, SfN published the History of Society for Neuroscience: 50th Anniversary podcast series. One guest was Dr. Marina Picciotto, who just finished her 7-year tenure as Editor-in-Chief at JNeurosci and is now the President-Elect of SfN. We hope you’ll enjoy this lightly edited version of her interview from 2019 as she reflects on the launch, growth, and future of JNeurosci.

Larry Squire and Tom Albright, coeditors of The History of Neuroscience in Autobiography book series, talk about their work collecting the personal narratives from researchers who have contributed to the field of neuroscience, and why this collection of stories is an important component of the historical record.

Presbycusis, a prevalent neurodegenerative disorder, is characterized by a decline in speech recognition ability. Recent studies have linked presbycusis with cognitive impairments across multiple domains. However, the underlying neurobiological mechanisms between presbycusis and cognitive impairments remain unclear. We assessed pure-tone audiometry thresholds (PTA), speech recognition thresholds (SRT), and cognitive abilities in individuals with presbycusis (24 males and 31 females) and healthy controls (23 males and 32 females). Using magnetic resonance imaging techniques, we calculated the amplitude of low-frequency fluctuations (ALFF) as a measure of functional characterization and gray matter volume (GMV) as a measure of structural characterization. Based on ALFF and GMV, we calculated Functional-Structural Ratio (FSR) to measure the functional-structural coupling. Significant correlations between GMV atrophy and ALFF changed in the putamen, fusiform gyrus, precuneus, and medial superior frontal gyrus ...

Microglia, resident immune sentinels in the brain, are crucial in responding to tissue damage, infection, damage signals like purines (ATP/ ADP), and clearing cellular debris. It is currently unknown how microglial reactivity progresses and contributes to seizure development following Theiler’s Murine Encephalomyelitis Virus (TMEV) infection. Previously, it has been demonstrated that purinergic signaling in microglia is disrupted in the hippocampus of TMEV-infected mice. However, whether reactive cortical microglia also exhibit changes in purinergic signaling, cytokine levels, and purinergic receptors are unknown. Thus, we seek to evaluate region-based differences in microglial reactivity in the TMEV model. We employed a custom triple transgenic mouse line expressing tdTomato and GCaMP6f under a CX3CR1 Cre promoter and exogenously applied ATP/ADP to acute brain slice preparations from TMEV-infected mice and controls of either sex. Interestingly and in contrast to what is observed in hippocampus, we found t...

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Organizing a “Nano” is a fantastic opportunity to network and connect with others in your field. Don’t know how to organize a nano or find others to participate? This webinar will review how to select a topic, identify others who might be interested in joining, and how to recruit others to join the nano.

Neuronline is a benefit of SfN membership. Renew your membership now to make sure you don’t lose access.

Neuronline is a benefit of SfN membership. Renew your membership now to make sure you don’t lose access.

Neuronline is a benefit of SfN membership. Renew your membership now to make sure you don’t lose access.