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1701 - 1710 of 52753 results
  • Article Scientific Research
    Exercise Motivation, Mood States, and the Dorsal Medial Habenula
    Our lab focuses on the development and function of a relatively obscure brain region called the habenula.
    Nov 3, 2016 Eric Turner, MD, PhD
  • Article Professional Development
    The Field Is Advancing. What's Most Exciting to You?
    Whether it’s improving quality of life or embracing the latest technology, the promise of an advancing field is motivation for many neuroscientists to pursue and support meaningful research.
    Oct 27, 2016
  • Article Professional Development
    5 Factors to Consider (Besides Research) When Applying to Graduate Programs
    As I outlined in a previous article, the first step in applying to graduate school is finding programs that match your research interests is. The next step is weighing other important factors that could impact your experience.
    Oct 27, 2016 Kavya Devarakonda
  • Article Training
    How to Develop Program Resources for a Variety of Career Paths
    Developing and assessing programs used to be a linear process because the training process was linear: graduate school, postdoctoral training, and academia.
    Oct 27, 2016 Ian Paul, PhD
  • Article Outreach
    Thinking on Your Feet: Tailoring Your Elevator Speech
    An elevator speech is one of your most important networking tools.
    Oct 25, 2016
  • Article Advocacy
    A Look at Advocacy: Measurable Change, Career Advancement, State Funding
    As an assistant professor at Columbia University, founder of the Greater New York City Chapter of SfN (braiNY), and active advocate for science funding, Haung (Ho) Yu’s perspectives on the benefits of outreach are far reaching.
    Oct 20, 2016
  • Video Diversity
    Recruitment Bias in Research Institutes
    Get an inside look at how unconscious bias during the recruitment process can negatively impact female applicants and how to proactively change the approach in this Institució CERCA video.
    Oct 20, 2016
  • Article Outreach
    Why Take Outreach Abroad? One Chapter’s Reason
    At the University of New England (UNE), we have invested in our community through both local outreach efforts in Maine and also through advancing the impact of global scientific and cultural exchange.
    Oct 18, 2016 Ed Bilsky, PhD
  • Article Career Paths
    My Journey Out of Academia ... and Back
    When I started my career, I assumed that I would always stay in academia.
    Oct 18, 2016 Jasna Markovac, PhD
  • Journal Article
    Histone-binding protein RBBP4 is necessary to promote neurogenesis in the developing mouse neocortical progenitors | eNeuro
    Chromatin regulation plays a crucial role in neocortical neurogenesis, and mutations in chromatin modifiers are linked to neurodevelopmental disorders. RBBP4 is a core subunit of several chromatin-modifying complexes; however, its functional role and genome-wide occupancy profile in the neocortical primordium are unknown. To address this, we performed RBBP4 knockdown using CRISPR/Cas9 on neocortical progenitors derived from mice of both sexes at embryonic age 12.5 during deep-layer neurogenesis. Our study demonstrates that downregulation of RBBP4 in the E12.5 neocortical progenitors reduced neuronal output, specifically affecting CTIP2-expressing neurons. We demonstrate that RBBP4 plays an essential role in regulating neocortical progenitor proliferation. However, overexpression of RBBP4 alone was not sufficient to regulate neuronal fate. Genome-wide occupancy analysis revealed that RBBP4 primarily binds to distal regulatory elements, and neuron differentiation is a significant GO biological pathway of RB...
    Nov 26, 2024 Sreeja Kumari Dhanya
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