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1621 - 1630 of 52753 results
  • Article Scientific Research
    The Four Purposes of Peer Review
    What is the job of a journal reviewer? Whether you’re looking to become a reviewer, just starting out, or want a refresher, here are the four major areas of responsibility of all peer reviewers.
    Feb 28, 2017 Margaret McCarthy, PhD
  • Journal Article
    The voltage-gated potassium channel Shal (Kv4) contributes to active hearing in Drosophila | eNeuro
    The full complement of ion channels which influence insect auditory mechanotransduction, and the mechanisms by which their influence is exerted, remain unclear. Shal (Kv4), a Shaker family member encoding voltage-gated potassium channels in Drosophila melanogaster , has been shown to localize to dendrites in some neuron types, suggesting a potential role for Shal in Drosophila hearing, including mechanotransduction. A GFP-protein trap was used to visualize the localization of the Shal channel in Johnston’s organ neurons responsible for hearing in the antenna. Shal protein was localized strongly to the cell body and inner dendritic segment of sensory neurons. It was also detectable in the sensory cilium, suggesting its involvement not only in general auditory function, but specifically in mechanotransduction. Electrophysiological recordings to assess neural responses to auditory stimuli in mutant Shal flies revealed significant decreases in auditory responses. Laser Doppler vibrometer recordings indicated a...
    Dec 17, 2024 Eli S. Gregory
  • Article Scientific Research
    The Ventral Midline Thalamus Orchestrates Hippocampal-Prefrontal Synchrony During Spatial Working Memory
    A growing body of evidence suggests that different types of learning and memory processes are distributed across specialized neural circuits consisting of two or more anatomically- and functionally-connected brain areas.
    Feb 23, 2017 Henry Hallock, PhD
  • Video Annual Meeting Scientific Research
    How to Engage Institutions to Publicly Support Animal Research
    Worldwide, researchers are engaging the public to increase their understanding of and support for animals in research.
    Feb 22, 2017
  • Video Annual Meeting Diversity
    How to Navigate Cultural Diversity
    Victoria Puig delivered the 2016 Celebration of Women in Neuroscience keynote speech. She shares her story of working abroad and returning home, while also recounting learning various communication and leadership styles, building networks, and learning language to advance in her career.
    Feb 22, 2017
  • Video Scientific Research
    Research Practices to Enhance Scientific Rigor
    Watch this video to learn about SfN’s positions on scientific rigor. Neuroscientists discuss best practices in experimental design, data analysis, and transparency in reporting and publishing methodology and data, and share how these efforts will strengthen the scientific foundation and ensure public confidence in the research being conducted.
    Feb 22, 2017
  • Podcast Scientific Research
    Podcast Series: The Perils of Publishing
    SfN's first-ever podcast series, The Perils of Publishing, explores the excitement, opportunities, and challenges of publishing. It is available to SfN members and non-members on Neuronline and iTunes (search for The Perils of Publishing and subscribe while you're there).
    Feb 22, 2017
  • Article Professional Development
    How to Choose Your Thesis Lab
    Choosing the laboratory in which you will do your thesis research is one of the most important and difficult decisions you will make in graduate school.
    Feb 21, 2017 Kavya Devarakonda
  • Journal Article
    Neonatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography | eNeuro
    Preterm infants are at risk for brain injury and neurodevelopmental impairment due, in part, to white matter injury following chronic hypoxia exposure. However, the precise molecular mechanisms by which neonatal hypoxia disrupts early neurodevelopment are poorly understood. Here, we constructed a brain-wide map of the regenerative response to newborn brain injury using high-resolution imaging-based spatial transcriptomics to analyze over 800,000 cells in a mouse model of chronic neonatal hypoxia. Additionally, we developed a new method for inferring condition-associated differences in cell type spatial proximity, enabling the identification of niche-specific changes in cellular architecture. We observed hypoxia-associated changes in region-specific cell states, cell type composition, and spatial organization. Importantly, our analysis revealed mechanisms underlying reparative neurogenesis and gliogenesis, while also nominating pathways that may impede circuit rewiring following neonatal hypoxia. Altogether...
    Dec 16, 2024 Nareh Tahmasian
  • Professional Development
    Oxytocin: The Hormone of Hype, Hope, and Healing
    Due to his work interrogating the role of certain chemicals in vole behavior at Yerkes National Primate Research Center, Larry Young has come across the problem of his results being portrayed hyperbolically, as the science sometimes goes to fictional lengths.
    Feb 16, 2017 Shweta Sahu
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